Miss A.S.D. Wickramasinghe

Natural products based drug development

Lecturer (Probationary)

Graduated with Bachelor of Pharmacy degree from University of Sri jayewardenepura in year 2015. Working as a Lecturer (Probationary) in OUSL since year 2018. Involved in Pharmacy education (government/ private sector) of Diploma/ Degree level , since year 2015. More interested in teaching aspects of Pharmaceutical Sciences. Research area of interest is natural product based drug development.

Pharmaceutical Sciences

Natural product based drug development, Nanoparticle based drug delivery

FMU3204-Pharmaceutical Microbiology I, FMU4306- Pharmaceutical Microbiology II, FMU5403- Pharmaceutical Technology I, FMU5205 – Pharmaceutical Analysis II, FMU5202 – Laws and Ethics for Pharmacy, FMU3204- Essential Mathematics for Pharmacy, BPU3232-Pharmaceutics III, BPU2223-Pharmaceutical Microbiology, BPU2127-Forensic Pharmacy

Wickramasinghe, A.S.D., Kalpitha, A.A.N., Perera,P.P.R., Chandrika, U.G. (2016) Effect of Traditional Cooking on In Vitro Bioaccessibility and Microstructure of β-Carotene and Starch, in Yellow-Fleshed Manihot esculenta, Journal of Food and Nutrition Sciences, 4 (4), 91-97.

Wickramasinghe, A.S.D., Kalpitha, A.A.N., Perera,P.P.R., Chandrika, U.G. (2018) A preliminary study on estimated glycaemic index and microstructure of starch, in boiled Cucurbita moschata (squash) found in Sri Lanka. International Journal of Advanced Research, 6 (5), 506-512

Ongoing Research:

  • Possible drug-drug interactions in prescriptions of discharged patients in a selected teaching hospital- Departmental research project carry out in Department of Pharmacy, OUSL- Acting as a co- investigator.
  • Assessment of undergraduate research knowledge of Allied Health Sciences students in Sri Lankan state universities-Joint research project conduct by members of Department of Pharmacy, Nursing and MLS in OUSL- Acting as a co-investigator.

Research articles
Wickramasinghe, A.S.D., Attanayake, A.P., Wijesiri, T.W., Peiris, H.H., Mudduwa, L.K.B., 2024. Pancreatic and hepatic histopathology of high-fat diet fed streptozotocin-induced Wistar rat model of type 2 diabetes mellitus. Ceylon Journal of Science, 53(2), pp. 235-242. https://doi.org/10.4038/cjs.v53i2.8274
Wickramasinghe, A.S.D., Kalansuriya, P., Attanayake, A.P., 2024. Gelatine nanoparticles encapsulating three edible plant extracts as potential nanonutraceutical agents against type 2 diabetes mellitus. Journal of Microencapsulation, 41(2), pp.94–111. https://doi.org/10.1080/02652048.2024.2313230
Wickramasinghe, A.S.D., Kalansuriya, P., Attanayake, A.P., 2023. Herbal extracts encapsulated nanoliposomes as potential glucose-lowering agents: an in vitro and in vivo approach using three herbal extracts. Journal of Pharmaceutical Sciences, 112 (2023), pp.2538-2551. https://doi.org/10.1016/j.xphs.2023.06.017.
Wickramasinghe, A.S.D., Kalansuriya, P., Attanayake, A.P., 2022. Biochemical characterization of high fat diet fed and low dose streptozotocin induced diabetic Wistar rat model. Journal of Pharmacological and Toxicological Methods, 113 (2022), p.107144.https://doi.org/10.1016/j.vascn.2021.107144..
Wickramasinghe, A.S.D., Kalpitha, A.A.N., Perera, P.P.R., Chandrika, U.G., 2018. A preliminary study on estimated glycaemic index and microstructure of starch, in boiled Cucurbita moschata (squash) found in Sri Lanka. International Journal of Advanced Research. 6 (May), pp. 506-512.
Wickramasinghe, A.S.D., Kalpitha, A.A.N., Perera, P.P.R., Chandrika, U.G., 2016. Effect of traditional cooking on in vitro bioaccessibility and microstructure of β-carotene and starch, in yellow-fleshed Manihot esculenta. Journal of Food and Nutrition Sciences, 4(4), 91-97. https://doi.org/10.11648/j.jfns.20160404.13
Review articles
Wickramasinghe, A.S.D., Kalansuriya, P., Attanayake, A.P., 2022. Nanoformulation of plant-based natural products for type 2 diabetes mellitus: From formulation design to therapeutic applications. Current Therapeutic Research, 96(2022), p.100672. https://doi.org/10.1016/j.curtheres.2022.100672.
Wickramasinghe, A.S.D., Kalansuriya, P., Attanayake, A.P., 2021. Herbal medicines targeting the improved β-cell functions and β-cell regeneration for the management of diabetes mellitus. Evidence-Based Complementary and Alternative Medicine, (2021), 2920530. https://doi.org/10.1155/2021/2920530.
Book chapter
Wickramasinghe, A. S. D., Attanayake, A. P. 2024. Chapter 5 – Chitosan-based nanomaterials, multiple forms, and characterization, Editor(s): N. Ali, M. Bilal, A. Khan, T.A. Nguyen, Chitosan-Based Hybrid Nanomaterials, Elsevier, pp. 91-106, ISBN 9780443218910, https://doi.org/10.1016/B978-0-443-21891-0.00005-6.
Conference proceedings
Wickramasinghe A.S.D., Attanayake A.P., Kalansuriya P. (2023, March). Nanoemulsions encapsulated with aqueous leaf extract of Coccinia grandis L. Voigt (Kovakka) as a potential nanonutraceutical agent against type 2 diabetes mellitus, Proceedings of the International Research Conference in Health Sciences 2023, University of Sri Jayewardenepura, Sri Lanka, p. 47.
Wickramasinghe A.S.D., Attanayake A.P., Kalansuriya P. (2023, June). Herbal extracts encapsulated gelatin nanoparticles as potential glucose-lowering agents, Proceedings of the 20th Academic Sessions, University of Ruhuna, Sri Lanka, p. 112.
Wickramasinghe, A.S.D., Attanayake, A.P., Kalansuriya, P. (2023, January). Histopathological changes in the pancreas of high-fat diet fed streptozotocin induced Wistar rats. Proceedings of the 10th Ruhuna International Science and Technology Conference, University of Ruhuna, Sri Lanka, p. 20
Wickramasinghe, A.S.D., Attanayake, A.P., Kalansuriya, P. (2021, January). Optimization and assessment of in vivo glucose-lowering activity of Cassia auriculata L. flower extracts encapsulated nanoliposomes. Proceedings of the Ruhuna International Science and Technology Conference, University of Ruhuna, Sri Lanka, p. 38.
Wickramasinghe, A.S.D., Attanayake, A.P., Kalansuriya, P. (2021, October). Optimization of high fat diet fed streptozotocin induced Wistar rat model for screening antidiabetic agents. Proceedings of the International Conference on Applied and Pure Sciences, University of Kelaniya, Sri Lanka, p.27
Wickramasinghe, A.S.D., Attanayake, A.P., Kalansuriya, P (2021, July). Glucose-lowering activity of Coccinia grandis (L.) Voigt leaf extract encapsulated nanoliposomes in Wistar rats induced with diabetes mellitus. Proceedings of the 3rd Conference, College of Biochemists of Sri Lanka, Sri Lanka, p. 49
Wickramasinghe, A.S.D., Attanayake, A.P., Kalansuriya, P (2021, March). Optimization of encapsulation efficiency of Coccinia grandis (L.) Voigt extract encapsulated nanoliposomes. Proceedings of the 18th Academic Sessions, University of Ruhuna, Sri Lanka, p. 95
Wickramasinghe, A.S.D., Attanayake, A.P., Kalansuriya, P. (2021, March). Effect of water: ethanol ratio on extraction yield, total polyphenol content and total flavonoid content of selected Sri Lankan medicinal plants. Proceedings of the 18th Academic Sessions, University of Ruhuna, Sri Lanka, p. 97